Yardbarker
x
Top MLB DFS Start‘em/Sit‘em For April 21st
- Mar 10, 2025; Port St. Lucie, Florida, USA; New York Mets shortstop Francisco Lindor (12) returns to the dugout during the third inning against the St. Louis Cardinals at Clover Park. Mandatory Credit: Reinhold Matay-Imagn Images

A new week is here for the baseball season, and today’s top MLB DFS lineups for cash prizes. Monday’s slate of eight games will start another exciting week of fantasy baseball for DFS players. With April ending next week, the second-to-last week of the first month of baseball could score today’s top MLB DFS lineups cash prizes.

Monday’s slate of games will kick off the week with a bang, featuring the New York Mets hosting divisional rivals, the Philadelphia Phillies. Another game that could have fantasy players win big on their top MLB DFS lineups today is the San Diego Padres, facing the Detroit Tigers.

April is ending in two weeks, and could have players win cash prizes in today’s top MLB DFS contests to end the month with style.

April 21st Top MLB DFS Lineup Starters

2B Luisangel Acuna, Philadelphia Phillies at New York Mets ($3,500 – DraftKings/2,500-Fanduel)

To start your Monday night top MLB DFS lineups, Luisangel Acuna of the New York Mets should be on the lineups. During the win over the Cardinals yesterday, Acuna went 2-4 with a run and a double to help sweep the Cardinals.

Acuna has been great for the Mets in his appearances and could have a great game against the Phillies. Being on a hot streak could help Acuna get a multi-hit for fantasy players.

OF Gavin Sheets, San Diego Padres at Detroit Tigers ($3,400 – DraftKings/2,700-Fanduel)

Gavin Sheets of the San Diego Padres should also be in their lineups for tonight’s top MLB DFS lineups. In the win against the Astros, Sheets went 1-4 with an RBI at Houston last night. Sheets has been a surprise for the Padres this season with a hot start and two home runs.

SS Bo Bichette, Toronto Blue Jays at Houston Astros ($4,300 – DraftKings/2,900-Fanduel)

The last player to have for your fantasy lineups is Bo Bichette of the Toronto Blue Jays for today’s DFS lineups. During the extra-innings loss against the Mariners, Bichette went 2-5 with an RBI.

Bichette has been on a five-game hitting streak and could extend the streak against a weak Astros team. Fantasy players could see another multi-hit game from the Blue Jays’ young star.

April 21st Top MLB DFS Benchwarmers

1B Matt Mervis, Cincinnati Reds at Miami Marlins (3,500 – DraftKings/3,200-Fanduel)

Matt Mervis is the first player who should be on your top MLB DFS fantasy benches this Monday night.

During the win over the Phillies, Mervis went 1-4 with a double, an RBI, two strikeouts, and a walk. Mervis has been decent but could have a long night against the Reds’ pitching staff. Fantasy players could see Mervis have a hitless game against the Reds’ starting pitching staff.

3B Nolan Arenado, St. Louis Cardinals at Atlanta Braves ($4,300 – DraftKings/3,200-Fanduel)

Another player who should be on your fantasy benches tonight is Nolan Arenado of the St.Louis Cardinals. Arenado did not play during the finale of the series against the Mets but struggled this past weekend.

The Cardinals’ third baseman went 2-8 with an RBI, three walks, and a strikeout. Arenado has been decent to start the season, but is on a cold streak and could have a hitless game for fantasy players.

OF Yodan Alvarez, Toronto Blue Jays at Houston Astros ($5,100-DraftKings/3,300-Fanduel)

The last player to bench for today’s top MLB DFS lineups is the Houston Astros’  Yordan Alvarez. During the close loss against the San Diego Padres, Alvarez went 0-3 with an RBI.

Alvarez has been on a cold start this season, barely producing power with only two home runs. The Astros slugger could have a long night against Toronto’s pitching. Fantasy players could see a multi-strikeout game from the Astros slugger.

Total Apex Media Stack Of The Night

Dec 12, 2024; Flushing, NY, USA; New York Mets right fielder Juan Soto poses for photos during his introductory press conference at Citi Field. Mandatory Credit: Brad Penner-Imagn Images

Monday’s top MLB DFS stacks of the day should be the New York Mets, Juan Soto, Pete Alonso, and Francisco Lindor. After sweeping the St. Louis Cardinals, the New York Mets have been getting great hitting from their stars. Soto yesterday had a multi-hit game, including three RBIs. The Mets’ superstar has been on a slow start, but has been heating up and could have another multi-hit game.

Alonso has also been on a tear to start the season, and could have another great game. With Aaron Nola pitching, fantasy players could see Alonso do well tonight, against his longtime foe, with a home run. Facing a pitcher whom he has been hot against, Alonso is no doubt a must-get for fantasy stacks.

Lindor has also been on a hot streak with a home run against the Cardinals’ pitching yesterday and during the weekend. With two home runs this past weekend, Lindor could have another one against the Phillies’ pitching. Fantasy players could have a fun Monday night with tonight’s top MLB DFS lineups and stacks.

This article first appeared on Total Apex Fantasy Sports and was syndicated with permission.

More must-reads:

Customize Your Newsletter

Yardbarker +

Get the latest news and rumors, customized to your favorite sports and teams. Emailed daily. Always free!