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Top MLB DFS Start‘em/Sit‘em For April 22nd
- Apr 12, 2025; Los Angeles, California, USA; Los Angeles Dodgers shortstop Mookie Betts (50) during the ninth inning against the Chicago Cubs at Dodger Stadium. Mandatory Credit: Kiyoshi Mio-Imagn Images

Top MLB DFS Start‘em/Sit‘em For April 22nd

Originally posted on Total Apex Fantasy Sports
By Jordan Ramos  |  Last updated Apr 22, 2025 3:24 AM ET

The MLB season is getting hot with the weather warming up, and today’s top MLB DFS lineups could help players win cash. Tuesday’s full slate of 15 games will keep this exciting week of fantasy baseball going for DFS players. April is getting warmer and could help players pick today’s top MLB DFS lineups and win cash prizes.

Tuesday’s slate of games will kick off the week with a bang, featuring the Atlanta Braves continuing their series against the St. Louis Cardinals. Another game that could have fantasy players win big on their top MLB DFS lineups today is the Los Angeles Dodgers, facing the Chicago Cubs.

April is ending in two weeks, and could have players win cash prizes in today’s top MLB DFS contests to end the month with style.

April 22nd Top MLB DFS Lineup Starters

C Logan O’Hoppe, Pittsburgh Pirates at Los Angeles Angels ($4,700 – DraftKings/3,100-Fanduel)

To start your Tuesday night top MLB DFS lineups, Logan O’Hoppe of the Los Angeles Angels should be on the lineups. During a walk-off win against the San Francisco Giants, O’Hoppe went 1-4 with two strikeouts. O’Hoppe could have a bounce-back game against the Pirates, who are horrid this season. The Angels’ star catcher could have a multi-hit game for fantasy players today.

1B/3B Wilmer Flores, Milwaukee Brewers at San Francisco Giants ($4,100 – DraftKings/3,200-Fanduel)

Wilmer Flores of the San Francisco Giants should also be in their lineups for tonight’s top MLB DFS lineups. In the win over the Brewers, Flores went 2-3 with a home run, a walk, and a run.

Flores has been on a tear for the Giants, leading the league with RBIs, and could have another great game. Fantasy players could see another home run from Flores against the lefty tonight.

2B Bryson Stott, Philadelphia Phillies at New York Mets ($4,400 – DraftKings/2,800-Fanduel)

The last player to have for your fantasy lineups is Bryson Stott of the Philadelphia Phillies for tonight’s DFS lineups. During the loss against the Mets last night, Stott went 2-5 with a home run, a run, and three RBIs.

Stott has been heating up for the Phillies, and against a rival, could have another multi-hit game. Fantasy players could see Stott have a home run and a chance to win cash prizes tonight.

April 22nd Top MLB DFS Benchwarmers

Mar 10, 2025; Port St. Lucie, Florida, USA; New York Mets shortstop Francisco Lindor (12) returns to the dugout during the third inning against the St. Louis Cardinals at Clover Park. Mandatory Credit: Reinhold Matay-Imagn Images

3B Eugenio Suarez, Tampa Bay Rays at Arizona Diamondbacks (4,500 – DraftKings/3,100-Fanduel)

Eugenio Suarez is the first player who should be on your top MLB DFS fantasy benches this Tuesday night. During a win against the Cubs on Sunday, Suarez went 1-1 in a pinch-hitting appearance.

Suarez has been inconsistent for the Diamondbacks this season and could struggle against the Rays. The Diamondbacks slugger could have a hitless game against the Rays tonight for fantasy players.

SS Francisco Lindor, Philadelphia Phillies at New York Mets ($4,900 – DraftKings/3,400-Fanduel)

Another player who should be on your fantasy benches tonight is Francisco Lindor of the New York Mets. During a win last night against the Phillies, Lindor went 2-3 with two home runs, four RBIs, and a walk.

Lindor has been getting hot for the Mets, but has struggled against Christopher Sanchez in his career. Fantasy players could see a multi-strikeout game from the Mets’ star infielder.

OF Christian Yelich, Milwaukee Brewers at San Francisco Giants ($4,800-DraftKings/3,600-Fanduel)

The last player to bench for today’s top MLB DFS lineups is the Milwaukee Brewers’  Christian Yelich. In the loss against the Giants, Yelich went 1-2 with two walks and a stolen base.

Yelich has been struggling for the Brewers this season and could have another rough night for DFS players tonight. DFS players could see a hitless game from the Brewers’ All-Star against a solid Giants pitching staff.

Total Apex Media Stack Of The Night

Tuesday’s top MLB DFS stacks for the night should be the Los Angeles Dodgers, Mookie Betts, Tommy Edman, and Freddie Freeman. The Dodgers have been a great team with a strong hitting core this season. Betts has been amazing for the Dodgers and could have a strong game tonight to start the series against the Cubs. Fantasy players could see Betts have a multi-hit game against the Cubs’ pitching staff tonight.

Edman has also been a bright spot for the Dodgers this season, with a great April to start the baseball season. Against a lefty tonight, Edman could have a multi-hit game from both sides of the ball. Fantasy players must get Edman in their fantasy stack tonight for a chance to win cash prizes.

Freeman could also have a great game against the Cubs’ pitching tonight with a potential home run for fantasy. Fantasy players could also see Freeman have a multi-hit game for fantasy. Fantasy players could have a great night with the top MLB DFS picks and stack tonight.

This article first appeared on Total Apex Fantasy Sports and was syndicated with permission.

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