Week 13's injuries included two quarterbacks and several other prominent NFL players. The following gallery features a rundown of the week's most significant injuries.
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Zach Ertz, TE, Eagles
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The Eagles struggled to score points on Sunday night, and the task become tougher when Ertz left with a concussion.
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C.J. Fiedorowicz, TE, Texans
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Fiedorowicz already missed time with a concussion earlier this season, and left Sunday's game to be evaluated for the same injury.
3 of 16
Leonard Johnson, CB, Bills
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It was a tough day for Bills cornerbacks. Johnson left with a knee injury, in addition to fellow Bills cornerback Tre'Davious White.
4 of 16
Shaq Lawson, DE, Bills
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Lawson left in the third quarter against the Patriots with an ankle injury. He was later carted to the locker room.
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Kyle Long, OG, Bears
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Long has had an injury-plagued season, and it continued on Sunday. He left the game with a shoulder injury.
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Levitre left early in Sunday's game with a triceps injury. He didn't return to the game.
7 of 16
Pernell McPhee, LB, Bears
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Chicago's linebacker depth was tested on Sunday when McPhee left with a shoulder injury in the first quarter and didn't return.
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Braxton Miller, WR, Texans
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Along with C.J. Fiedorowicz, Miller left Sunday's game with a concussion.
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Ogletree made a big interception early in Sunday's game but left later with an injured elbow and didn't return.
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Cleveland first-round rookie Peppers left Sunday's game with a knee injury. The severity of the injury hasn't been released.
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Tennessee lost their starting cornerback on Sunday due to a concussion. He will be in the concussion protocol this week.
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Smith was lost for the season with a torn Achilles tendon after leaving in the second quarter on Sunday.
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Stafford left in the fourth quarter of Sunday's game with a bruised hand. Fortunately, X-rays were negative following the game.
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Tankersley had a tough day on Sunday. He left early in the game with a shoulder injury before returning. Later, he left the game again with an ankle injury.
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Tyrod Taylor, QB, Bills
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Taylor suffered a knee injury early in Sunday's game and left in the fourth quarter. The Bills are unsure about his status going forward.
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Tre'Davious White, CB, Bills
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White was injured on Sunday when Patriots tight end Rob Gronkowski hit him in the head while on the ground in a dirty play. He left the game with a concussion.